HIGH-RESOLUTION ANALYSIS OF COPY NUMBER ALTERATIONS AND ASSOCIATED EXPRESSION CHANGES IN OVARIAN TUMORS

Abstract Background DNA copy number alterations Clothing Set are frequently observed in ovarian cancer, but it remains a challenge to identify the most relevant alterations and the specific causal genes in those regions.Methods We obtained high-resolution 500K SNP array data for 52 ovarian tumors and identified the most statistically significant mi

The major progress made in the identification of the molecular bases of mitochondrial disease has revealed the huge diversity of their 3 Piece Outdoor Sofa origin.Today up to 300 mutations were identified in the mitochondrial genome and about 200 nuclear genes are possibly mutated.In this review, we highlight a number of features specific to mitoch